Insightec’s neurosurgery solution, Exablate Neuro, is the first focused ultrasound device approved by the FDA to treat patients with essential tremor. Exablate Neuro is a non-invasive, image-guided personalized thalamotomy, treated through an intact skull that doesn't require any ionizing radiation, incisions or implants.

High intensity focused ultrasound waves precisely target a focal point in the Vim nucleus of the thalamus, the tiny part of the brain that is thought to be responsible for causing tremors. The Exablate Neuro ultrasound transducer consists of 1024 beams that generate enough heat to ablate the targeted tissue during treatment. The result is an immediate and significant reduction of tremor for patients. If you are a patient, please click here for more information:


How IT Works

Exablate Neuro is a non-invasive, image-guided alternative for deep brain lesioning

FDA labeling

The Exablate Neuro is intended for use in the unilateral Thalamotomy treatment of idiopathic Essential Tremor patients with medication-refractory tremor. Patients must be at least age 22. For Exablate Neuro FDA Labeling CLICK HERE.


RISKS - Risks associated with thalamotomy include transient and/or permanent sensory paresthesias, numbness, imbalance, and/or gait disturbance. Risks and adverse events also associated with the Exablate Neuro treatment include sonication-related pain, sonication-related dizziness or nausea or potential for deep vein thrombosis associated with 3-4 hours on the treatment bed.

    • Essential Tremor
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Why INSIGHTEC Neurosurgery?

  • Clinical Value

    Non-invasive, no penetrating trajectories and no ionizing radiation. Real time MRI for targeting and thermal feedback. Sharp, accurate treatment that allows for lesions as small as 2mm.

  • Patient Value

    No craniotomy, immediate results, minimal risk of infection, bleeding or other surgical complications. Single session treatment, no anesthesia, quick recovery and no implanted hardware.

  • Operational efficiency

    Short hospitalization. Medical facilities can attract and treat additional patient groups and strengthen their hospital/clinic leadership in innovation and advanced care.

Physician Testimonials

Watch Garth Rees Cosgrove, MD, W. Jeffrey Elias, MD and Ryder P. Gwinn, MD, as they talk about their experience with INSIGHTEC's Exablate Neuro for the treatment of essential tremor including the innovative technology, the MRgFUS technique, side effects and more.

Prof. Takaomi Taira, Director of Stereotactic and Functional Neurosurgery, Dep. Of Neurosurgery, Tokyo Women's Medical University, Tokyo, Japan, shares his insights regarding the advantages of Exablate MRgFUS technology in treating movement disorders, and the witnessed change in patients’ quality of life.

Regulatory Approvals

Per Indication

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