INSIGHTEC’s Exablate Prostate is an MR-guided focused ultrasound treatment designed to maximize precision and optimize control for the focal treatment of locally-confined prostate cancer.
What is Exablate Prostate?
MR imaging and thermometry provide real-time monitoring to allow continuous adjustment of treatment parameters according to need. This ensures that sufficient heat is delivered at the target while avoiding adjacent vulnerable structures.
The movable endorectal focused ultrasound transducer with nearly 1,000 ultrasound rays generates an adjustable focus that can ablate cancerous tissue throughout the prostate gland.
The sharp margin of the ultrasound beam allows targeting of tumors within less than 1 mm of the sphincters and neurovascular bundles, with no heat applied to these structures. The active rectal cooling system further safeguards the rectal wall.
Final assessment with contrast MRI provides immediate verification of complete ablation.
Targeted ablation, high resolution MR visualization and flexible planning software are designed to deliver a focal prostate treatment precisely tailored to the individual patient, reducing treatment risks while optimizing results.
Locally Confined Prostate CancerRead More close
INSIGHTEC uses MR guided Focused (MRgFUS) as a minimally-invasive thermal ablation technique to ablate locally confined prostate cancer. MRgFUS destroys prostate cancer tissue using a thermal effect.
Ultrasound energy is focused onto the prostatic cancer, heating the targeted tissue at a temperature above 55ºC for a few seconds. This heating of the tissue results in local coagulation and necrosis of the heated cells. A single application of the energy is called a ‘sonication’ and a typical treatment is comprised of multiple ’sonications’. Sonications are repeated until the entire volume of the cancer has been treated. Immediately post treatment, the physician can evaluate the treatment results by using a contrast agent which indicates the extent of the volume of cancerous tissue that was successfully treated.
Prostate CancerRead More close
This study is intended to show that ExAblate™ MRgFUS is a safe procedure that can significantly postpone or eliminate the need of patients with organ confined intermediate risk prostate cancer to undergo a definitive treatment (i.e., Radical Prostatectomy or Radiation therapy) for their disease. For more information CLICK HERE.
Why INSIGHTEC Urology
Sharp margins between ablated tissue and adjacent structures. Real time thermal feedback for continuous monitoring and adjustment. Immediate assessment of treatment outcome. No risk of re-treating.
Focal treatment; MR imaging for target identification and verification designed to minimize damage to prostatic and peri-prostatic functional structures; Minimally-invasive; Single treatment allows fast recovery and return to normal activity.
Attractive for patients; Medical facilities can attract and treat additional patient groups and strengthen their hospital/clinic leadership in innovation and advanced care.
Locally Confined Prostate CancerApproval Country Year
- European CE Mark