INSIGHTEC enters the exciting field of Neurosurgery with Exablate Neuro. Exablate Neuro is the first focused ultrasound device approved by the FDA to treat medication refractory essential tremor patients with non-invasive MR-guided focused ultrasound thalamotomy.

What is Exablate Neuro?

Exablate Neuro is an innovative medical device that uses focused ultrasound together with MR imaging to precisely target and treat a target deep within the brain through an intact skull.

To treat essential tremor, the Vim nucleus of the thalamus has been identified as the target responsible for causing tremors. The Exablate Neuro ultrasound transducer focuses 1024 ultrasound waves to generate enough heat to ablate the targeted tissue. The result is an immediate and significant reduction of hand tremor for patients.

The MRgFUS procedure is called Neuravive. During planning and treatment, the patient lies on the Exablate Neuro treatment bed within an MRI scanner. MRI provides high resolution visualization, patient-specific treatment planning and continuous monitoring of the procedure. Real-time thermal feedback allows the physician to control and adjust the focused ultrasound treatment, ensuring that the targeted tissue is completely ablated.

If you are a patient, please click here for more information:


How IT Works

Exablate Neuro - non-invasive, image-guided alternative for deep brain lesioning

    • Essential Tremor (ET)
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Why INSIGHTEC Neurosurgery?


    Non-invasive MR-guided focused ultrasound thalamotomy provides anatomical localization and physiological verification for fine tuning of the target before final ablation. MR imaging delivers high resolution anatomical imaging as well as real-time thermal feedback for treatment monitoring. This innovative technology has been developed to allow sub-millimeter target movement and lesions as small as 2mm for treatment control.


    The Neuravive procedure is performed without a craniotomy and with no implanted hardware, minimizing or eliminating the risk of bleeding and infection. The patient is awake and able to see and experience the immediate results. The treatment is performed in a single session, and patients return to normal activity within days


    Focused ultrasound is performed in an MRI suite and often on an outpatient basis. Within the hospital workflow, there is no need for a surgical suite, and patients often go home the same day. Incision-less surgery all but eliminates the risk of infection and bleeding while reducing the time a patient spends recovering.

Physician Testimonials

Watch Garth Rees Cosgrove, MD, W. Jeffrey Elias, MD and Ryder P. Gwinn, MD, as they talk about their experience with INSIGHTEC's Exablate Neuro for the treatment of essential tremor including the innovative technology, the MRgFUS technique, side effects and more…

Prof. Takaomi Taira, Director of Stereotactic and Functional Neurosurgery, Dep. Of Neurosurgery, Tokyo Women's Medical University, Tokyo, Japan, shares his insights regarding the advantages of Exablate MRgFUS technology in treating movement disorders, and the witnessed change in patients’ quality of life.

Regulatory Approvals

Per Indication

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