MR guided Focused Ultrasound Surgery (MRgFUS): What is it?

Highly localized treatment targets tumor while sparing surrounding tissue

ExAblate using MRgFUS: The Operating Room of the Future

The incisionless, outpatient treatment

MR guided Focused Ultrasound Surgery (MRgFUS) technology combines a high intensity focused ultrasound beam that heats and destroys targeted tissue, non-invasively and Magnetic Resonance Imaging system (MRI) which visualizes patient anatomy, and controls the treatment by continuously monitoring the tissue effect.

Why Are MR guided Focused Ultrasound and Control Important for a Non-Invasive Procedure?
MRgFUS provides:

  • Imaging in 3 orientations for precise tumour targeting and accurate identification of pathology
  • Beam path visualization for controlled treatment
  • MR thermometry for real-time and continuous temperature feedback allowing the physician to see temperature changes in the tumour during treatment
  • Post treatment contrast imaging for precise treatment validation

All of the above ensure safe and accurate MR guided Focused Ultrasound treatments.

Imaging in 3 Orientations for Precise tumour Targeting
High precision anatomical MR images in 3 orientations, showing the tumour and surrounding organs, are used to position the patient and to plan the treatment to ensure:
- exact tumour targeting
- beam path visualization.


MR guided Focused Ultrasound (MRgFUS) Clinical Photos
Sagittal clinical photo  Axial clinical photo  Coronal clinical photo
        Sagittal                                   Axial                                   Coronal

Beam path visualization 
MR guided Focused Ultrasound beam 
With MRgFUS, the focused ultrasound beam can be seen during the treatment to ensure that the ultrasound travels through a safe pathway to the focus. This ensures that the correct region is targeted.  Sonication parameters can be adjusted to optimize the treatment and are monitored by the physician during the treatment.


MR thermometry for continuous temperature feedback
HIFU thermal ablation
The temperature is continuously monitored during every sonication providing accurate thermal monitoring of the targeted ablation.


Temperature maps display the relative tissue temperature as a color map superimposed on an anatomical MR image. This allows the physician to observe temperature changes continuously during treatment. Based on these observed temperature changes, treatment parameters can be adjusted to ensure safe and effective thermal ablation.

Accumulated thermal dose
MRgFUS – HIFU clinical photo
The system keeps track of which regions have reached thermal dose enabling the physician to determine if there has been sufficient heating.


Outcome assessment - post treatment contrast imaging for precise treatment validation
Uterine Fibroids HIFU Ablation
This image shows two uterine fibroids that have been successfully ablated with MRgFUS.



 

Illustration of how multiple high-intensity ultrasound waves converge on the precise targeted point in the brain‚and the heat build-up only in the focuse‚ and not in the surrounding tissue
Illustration of how multiple high-intensity ultrasound waves converge on the precise targeted point in the brain‚and the heat build-up only in the focuse‚ and not in the surrounding tissue
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