Caution - Investigational Device - Limited by United States Law to Investigational Use.
The neuro research programs and future potential applications include:
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- Brain tumors - Neurological disorders
- Clot Lysis for stroke
- Targeted drug delivery
Using ExAblate for Neurosurgery applications
The ExAblate device for treating neurosurgery applications consists of a unique “helmet” like apparatus consisting of thousands of individual ultrasound elements. Neurosurgery treatments using focused ultrasound technology present two unique challenges. First, the high ultrasound absorption in bone (as described in the section on bone metastases) results in an increase in bone temperature which may result in brain-tissue coagulation near the skull. As a result, chilled water is constantly circulated around the skull during the treatment. Secondly, the skull has a variable thickness and density which results in the ultrasound beam being defocused. CT images are used to reconstruct the skull, and this data is used to configure the ultrasound beams coming from the phased array transducer to be properly focused at the targeted lesion.
- Non-Invasive Transcranial treatment
- No ionizing radiation effects enables repeated treatments with no long term toxicity
- Thermal ablation provides immediate bio-physical tissue response
- Intraoperative image guidance allows for target localization with 1mm accuracy
